%0 Journal Article %T Comparison of SARS-CoV-2 (Coronavirus) with other Similar Viruses Based on Current Evidence %J Journal of Iranian Medical Council %I Iran Medical Council %Z 2645-338X %A Kianzad, Shaghayegh %A SeyedAlinaghi, SeyedAhmad  %A Asadollahi-Amin, Ali %A Dadras, Omid %A Karimi, Amirali %A Masoud Afsahi, Amir %A MohsseniPour, Mehrzad %A Barzegary, Alireza %A Mirzapour, Pegah %A Mirghaderi, Seyed Peyman %A Salehi, Mohammad Amin %A Pashaei, Zahra %A Nazeri, Zahra %A Behnezhad, Farzane %A Ali, Zoha %A Noori, Teyebeh %A Mehraeen, Esmaeil %A Sabatier, Jean-Marc %A Jahanfar, Shayesteh %D 2022 %\ 01/01/2022 %V 5 %N 1 %P 4-26 %! Comparison of SARS-CoV-2 (Coronavirus) with other Similar Viruses Based on Current Evidence %K Behavior %K COVID-19 %K Gene expression %K SARS-CoV-2 %K Sequence %K similarity %R http://dx.doi.org/10.18502/jimc.v5i1.9565 %X The rapid spread and high mortality rate of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) have recently received worldwide attention. Understanding the pathologic features and behavior of this new virus can help control its spread. The present study aimed to compare SARS-CoV-2 with other similar viruses.This study is a systematic review of current evidence conducted in September 2020. A search was carried out utilizing the keywords in the online databases, including Google Scholar, PubMed, Scopus, Science Direct, and Web of Science. The original peer-reviewed papers written in English that met the eligibility criteria were included in the final report.In this study, we compared SARS-CoV-2 with similar viruses such as influenza, Zika, Ebola, HIV, SARS-COV, and Middle East Respiratory Syndrome Coronaviruses (MERS-COV) in the features such as envelope structure, risk factors, duration of the disease, common symptoms, and treatments. Moreover, Coronavirus Disease 2019 (COVID-19) has many similarities with the other viruses explained in the present study. However, there are still controversies about the virus’s behavior.Although there are similarities between the abovementioned viruses, the scientific community should also pay special attention to distinct features of SARS-CoV-2, particularly the high probability of transmission in the human population, which causes substantial morbidity and mortality worldwide. Future studies are needed further to explore the biological and epidemiological behavior of this virus. %U http://www.jimc.ir/article_151333_fa8a56b6b4b7eaba74f190048905f456.pdf